Worried About Infertility? M2 Tone is Here to Help

M2 TONE is a non-hormonal menstrual modulator that corrects all menstrual irregularities. M2 TONE is a uterine tonic that improves endometrium (inner wall of uterus) parameters and hence enhances implantation rate in unexplained infertility, anovulatory infertility and ART protocols like IUI, IVF, ICSI, etc.

Menarche announces the fertility journey in females. In some cases, menstrual irregularities such as dysmenorrhea, oligomenorrhea and amenorrhea may present itself right from adolescence and young adulthood and any prolonged inadequacies or irregularity in the menstrual pattern may hinder fertility later in life.

M2 TONE maintains the natural balance between hormones, nutrition and emotions thereby making more women complete through motherhood.

Internationally Researched Ingredients and their roles

·       Saraca indica and Symplocos racemosa regularizes menstrual cycle and flow and also corrects ovarian insufficiency.
·       Mesua ferrea restores hormonal balance.
·       Shuddha kasis acts as hematinic and helps to maintain Hemoglobin levels.
·       Zingiber officinale relieves dysmenorrhea.
·       Withania sominifera relieves anxiety.

How does M2 TONE help in treating Menstrual Irregularities and Infertility?

Menstruation is a periodic flow of blood and cells from the lining of the uterus excreted out through the vagina, generally it follows the cycle of every 28 to 32 days. The complete cycle of menstruation is controlled by the important centers in the body which regulate hormonal balance. These centers are the hypothalamus in the brain, the pituitary gland and the ovaries. This balancing system is collectively known as HPO (Hypothalamus – Pituitary – Ovarian) axis. It controls the levels of estrogen (the hormone that prepares the lining of the uterus) and progesterone (the hormone that helps maintain a pregnancy). The natural rhythm of the menstrual cycle may be temporarily disturbed by hormonal imbalance, malnutrition, illness, or emotional disturbances. These lead to irregular, heavy menstruation (Dysfunctional Uterine Bleeding – DUB), painful menstruation (dysmenorrhoea), scanty menses (oligomenorrhoea), absence / complete cessation of menses during fertile age (amenorrhoea).

S. indica acts by competitive inhibition of estrogen receptors. By this mechanism, it normalizes hormone levels, thus correcting and restoring the balance of the disturbed HPO axis, this then corrects the menstrual cycle irregularity10.
S. racemosa exhibits estrogenic activity which maintains the structural and functional integrity of the endometrium which consequently regulates the menstrual flow.

M2 TONE is effective in both scanty and excessive menstrual bleeding i.e. if estrogen levels are low, it will increase it and when the levels are high, it will decrease it. The net effect will be to normalize hormone levels.

M. ferrea improves endocrinal function which leads to restoration of hormonal and emotional balance and also relieves emotional stress4. M2 TONE is effective in making the endometrium more favorable to implantation.

All infertility procedures like IUI, IVF etc. only ensure fertilization but does not guarantee endometrial implantation, this can be a limiting factor and may explain the high failure rate seen in infertility treatment and consequently resulting in financial, emotional and physical strain on the patient. Therefore, every effort should be made to ensure higher implantation and pregnancy rate.

M2 TONE improves blood supply to endometrium by lowering the Pulsatility Index (resistance to endometrial vascularity). Increased blood supply ensures a healthy endometrium.

M2 TONE causes endometrial proliferation by enhancing glycogen content of endometrium thus optimising the endometrial thickness. A uniform thickness is essential for successful implantation, nidation and successful continuation of pregnancy thereafter.

M2 TONE improves overall uterine score (scale for examining uterine receptivity). Better the score, better the chances of conception and assurance of successful implantation and pregnancy outcomes.

Additional Benefits of M2 TONE
·       Ensures treatment of menstrual irregularities without any deleterious effects on the growth of adolescent girls
·       Can be prescribed along with hormones
·       No drug interactions with any of the hormonal preparations, analgesics, or any other drugs available in the market
·       Unlike hormonal treatment, long-term use of M2-Tone doesn’t have adverse effect of epiphyseal ossification
·       Contains Withania sominifera which helps to relieve anxiety3.

How should M2 TONE be taken?
For DUB – 15mls or 2 tabs twice daily for 3 to 6 menstrual cycles.
For Unexplained Infertility – 15mls or 2 tabs twice daily till conception occurs.
For Anovulatory Infertility – 15mls or 2 tabs twice daily, 3 weeks prior to induction of clomiphene citrate.
For ART Protocols – 15mls or 2 tabs twice daily from day of down regulation till embryo transfer.